Dr. Ikeda thinks that Flower may have had lymphosarcoma, or lymphoma. Her liver and kindey where spotted, and he looked at samples of these tissues under microscope. He emphasized that he is not a pathologist, but he suspected that Flower had developed this cancer. It can act quickly, as it is blood borne.
Dr. Ikeda also said that her intestine was essentially swollen in a few areas and was not as soft as it should be. This is was also the case for the pylorus from the stomach to the small intestine. It is likely that it was difficult for her to pass food from her stomach to her intestine because of the problem with this valve.
Flower was also completely spayed, having had all of her reproductive organs removed. We cannot know, then, whether she may have ever had kittens or not. One of the few things we do know about her previous life is that she must have been overweight because she was placed on a weight-reducing diet at the shelter before we got her.